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The Mediterranean diet is famous for its health benefits and now also for its role in fertility. If you’re starting an in vitro fertilization (IVF) treatment, take note! A diet rich in fruits, vegetables, legumes, fish, and olive oil provides key nutrients that can increase your chances of success. What is the mediterranean diet and why does it matter in IVF? It’s based on fresh, natural foods: fruits, vegetables, whole grains, legumes, nuts, fish, and extra virgin olive oil. It includes dairy and lean meats in moderate portions and limits sugars and saturated fats. This way, you get antioxidants, omega-3 fatty acids, fiber, and micronutrients that improve egg quality, embryo development, and endometrial health. How does it improve egg and embryo quality? Studies show the Mediterranean diet: Reduces oxidative stress with antioxidants (vitamins C and E). Supports mitochondrial function with omega-3 fatty acids (EPA and DHA). Promotes healthy cell division thanks to folate. Key nutrients for fertility Antioxidants: vitamins C (ascorbic acid) and E (tocopherol). Omega-3: 1–2 g/day from fish or flaxseed. Folate: 400 µg/day from leafy greens and legumes. Monounsaturated fats: 20–40 mL/day of extra virgin olive oil. Incorporate the mediterranean diet today Choose seasonal produce, use 30–40 mL of extra virgin olive oil daily, and eat fish (salmon, sardines) 2–3 times a week (150 g per serving). Swap refined grains for whole grains—quinoa, farro, or whole wheat bread—snack on a handful (30 g) of nuts or seeds, and add 100 g of cooked legumes. A healthy, sustainable lifestyle Besides improving fertility, this diet protects your heart, regulates blood sugar, and reduces the risk of certain cancers. Prioritize plant-based foods, minimize processed items, and practice mindful eating. How Ingenes supports your nutrition At Ingenes we understand that nutrition is crucial in IVF. Our team guides you with personalized plans, integrating dietary counseling and advanced reproductive techniques. Discover the secret to successful IVF. The importance of balanced nutrition A well-balanced meal plan ensures essential macro and micronutrients for healthy eggs, quality embryos, and a receptive endometrium. More details at “The Importance of Nutrition in Fertility Treatment”. Practical tips for your reproductive health Fruits and vegetables: 5 servings daily. Lean proteins: 1.2–1.5 g/kg body weight (fish, poultry, legumes). Healthy fats: 20–35% of daily calories. Hydration: 2–2.5 L of water per day. Frequently Asked Questions 1. How long until I see changes? Following the diet for 3–6 months before IVF improves oocyte and embryo quality. Antioxidant levels rise in weeks, while lipid profiles and inflammatory markers stabilize over months. Consistency and gradual changes are key to regulating hormones, maintaining stable cycles, and optimizing endometrial receptivity. 2. What if I have dietary restrictions? The Mediterranean diet is flexible. If you’re vegan or vegetarian, increase legumes (100–150 g cooked) and nuts (30 g). For omega-3, use chia seeds or algae supplements. If lactose intolerant, choose fortified plant-based milks. Always consult your specialist or a dietitian. 3. What should I avoid in IVF? Limit red meat to under 300 g/week and avoid processed foods. Reduce sweets, refined grains, caffeine (≤200 mg/day), and alcohol. Opt for whole, colorful foods. 4. Why does olive oil help implantation? Extra virgin olive oil provides oleic acid and polyphenols that improve blood flow and reduce endometrial inflammation. With 20–40 mL daily, you promote a thicker, healthier uterine lining. Sources Consulted Martínez-González, M. A., & Estruch, R. (2021). Mediterranean diet, cardiovascular disease and mortality: a critical review. European Journal of Internal Medicine, 82, 1–3. https://doi.org/10.1016/j.ejim.2020.10.004 Gaskins, A. J., & Chavarro, J. E. (2018). Diet and Fertility: a review. American Journal of Obstetrics and Gynecology, 218(4), 379–389. https://doi.org/10.1016/j.ajog.2017.11.587 National Library of Medicine. (2022). Antioxidants and Reproductive Biology. MedlinePlus. https://medlineplus.gov/antioxidantsandreproductivehealth.html Thompson, J., & Hanna, J. (2020). Omega-3 Fatty Acids in Reproductive Health. Fertility and Sterility, 114(5), 987–993. https://doi.org/10.1016/j.fertnstert.2020.07.010 We know the journey to parenthood can be challenging. You’re not alone: every step counts. If you seek guidance and support, consult a fertility specialist for a personalized, professional plan to accompany you on this journey.

The path to motherhood can present challenges, and one of them is polycystic ovary syndrome (PCOS), more common than you might think. At Ingenes, we understand its effects on fertility and offer personalized solutions to accompany you in your dream of becoming a mother. What Is PCOS and how does It affect fertility? PCOS, which affects 5–10% of women of reproductive age, is characterized by irregular menstrual cycles, weight changes, acne, excess hair growth, and small cysts on the ovaries. This hormonal imbalance (LH, FSH, and androgens) can disrupt ovulation and reduce your chances of conceiving. Personalized treatments for PCOS Every case is unique. At Ingenes, we design your plan according to your hormonal profile and reproductive goals. We may use clomiphene or letrozole to induce ovulation, metformin (500–2,000 mg/day) to improve metabolic function, and guide you on nutrition, exercise (150 minutes/week), and weight loss (5–10%) to restore your cycles. Never self-medicate: always consult a Reproductive Medicine specialist before taking any medication. Advanced PCOS technologies In our laboratory we use time-lapse to monitor embryo development, PGT-A to rule out genetic abnormalities, and stimulation protocols tailored to PCOS. We track your response with transvaginal ultrasounds and blood estradiol measurements. IVF: an effective option In vitro fertilization bypasses ovulatory dysfunction: we stimulate your ovaries, retrieve multiple eggs, fertilize them, and transfer the highest-quality embryo. At Ingenes, PCOS success rates exceed 60% per cycle thanks to personalized dosages and advanced vitrification. Emotional support along the way You are not alone. We know facing PCOS and treatments can be exhausting. That’s why we offer psychological counseling and support groups to accompany you with empathy and understanding. Lifestyle and fertility A Mediterranean diet—rich in vegetables, lean proteins, and healthy fats—along with regular exercise improves insulin sensitivity and balances your hormones. Losing 5 kg can restore ovulation. Practicing mindfulness helps reduce stress and regulate your cycles. The future with PCOS PCOS doesn’t wreck your dream of becoming a mother. With advances in reproductive medicine and our personalized approach, more and more women achieve pregnancy. Visit Polycystic Ovary Syndrome: What You Should Know and read real success stories: “Women with Polycystic Ovary Syndrome Can Have Children”. Frequently Asked Questions Can I Conceive Naturally If I Have PCOS? Yes. Regularizing your cycle with diet, exercise, and weight control often restores ovulation. Tools like basal body temperature or LH tests help you identify your fertile window. If you need more support, treatments such as clomiphene or letrozole induce ovulation in 70% of cases and achieve conception in 30–40% after six cycles. What Are the Side Effects of Medications for PCOS? Clomiphene may cause hot flashes, mood swings, or ovarian enlargement. Metformin can cause nausea, diarrhea, or abdominal pain, especially if you exceed 1,500 mg/day. Starting with low doses and increasing gradually reduces these effects. Your doctor will monitor your health with tests and ultrasounds. How Does Weight Loss Improve PCOS Symptoms? Losing 5–10% of your weight decreases insulin resistance, lowers androgens, and restores ovulation. Combine aerobic exercise (30 minutes, 5 days/week) with strength training. A low–glycemic index meal plan stabilizes your blood sugar and protects your long-term health. Is IVF Safe for Women with PCOS? Yes. Low-stimulation or antagonist protocols reduce the risk of ovarian hyperstimulation syndrome. We adjust gonadotropin doses based on your estradiol and follicle count. Studies show IVF does not increase congenital malformations or obstetric complications in children born to patients with PCOS. Sources NIH. (2023). Polycystic Ovary Syndrome. MedlinePlus. Teede H. J. et al. (2018). Recommendations from the International PCOS Network. Human Reproduction. Rojas J. et al. (2014). Polycystic Ovary Syndrome: Evidence-Based Overview. Clinical Medicine Insights: Reproductive Health. American Society for Reproductive Medicine. (2020). ASRM Practice Committee Guidelines: PCOS. Fertility and Sterility. Remember that every journey is unique. We are here to support and guide your path to motherhood. Consult an assisted reproduction specialist to design the best plan for you.